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Predicting the potential for zoonotic transmission and host associations for novel viruses

Pandit PS, Anthony SJ, Goldstein T, Olival KJ, et al., Johnson CK. Communications Biology. 2022 Aug 19; 5:844.

Our virus-host association network predicts spillover risk and potential hosts for novel viruses detected in wildlife.

This research predicts zoonotic transmission risk and potential hosts for 531 novel animal viruses, primarily of wildlife origin, based on virus-host associations of known viruses, improving our understanding of the ecology of newly discovered viruses to inform on and prioritize them for further characterization.

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Global shifts in mammalian population trends reveal key predictors of virus spillover risk

Johnson CK, Hitchens PL, Pandit PS, Rushmore J, Evans TS, Young CC, Doyle MM. Proceedings of the Royal Society B: Biological Sciences. 2020 Apr 8; 287(1924): 20192736.

The same processes that threaten wildlife populations increase virus spillover risk.

This research identified a higher incidence of zoonotic viruses in mammalian species that have declined in abundance due to habitat loss, fragmentation, and exploitation, providing direct evidence for the impact of environmental change on emerging infectious disease.

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